Rabbit Secondary Antibodies
ABclonal Technology PE Rabbit anti-Mouse CD200/OX2
Predicted to enable protein binding activity involved in heterotypic cell-cell adhesion Involved in negative regulation of cell population proliferation negative regulation of macrophage activation and negative regulation of neuroinflammatory response Located in cell surface Is expressed in several structures including anterior naris aorta bone nervous system and retina Used to study autoimmune disease Orthologous to human CD200 (CD200 molecule)
ABclonal Technology PE Rabbit anti-Mouse CD11a mAb
Predicted to enable ICAM-3 receptor activity and cell adhesion molecule binding activity Involved in cell-cell adhesion Acts upstream of or within several processes including activated T cell proliferation positive regulation of T cell proliferation and positive regulation of calcium-mediated signaling Located in cell-cell junction external side of plasma membrane and immunological synapse Is expressed in heart hemolymphoid system and vault of skull Orthologous to human ITGAL (integrin subunit alpha L)
ABclonal Technology PE Rabbit anti-Mouse S100A9
Predicted to enable calcium ion binding activity and calcium-dependent protein binding activity Involved in peptidyl-cysteine S-nitrosylation positive regulation of blood coagulation and regulation of translation Acts upstream of or within several processes including actin cytoskeleton reorganization astrocyte development and regulation of integrin biosynthetic process Predicted to be located in cell junction cytosol and nucleoplasm Predicted to be active in cytoplasm extracellular space and nucleus Is expressed in several structures including jaw liver otic capsule skeleton and spleen red pulp Human ortholog(s) of this gene implicated in myocarditis Orthologous to human S100A9 (S100 calcium binding protein A9)
ABclonal Technology APC Rabbit anti-Mouse IgG1 mAb
Mouse IgG1 is a subtype of immunoglobulin G antibody that is produced by B cells in response to an antigen It is the most abundant IgG subtype in the serum and plays a crucial role in the adaptive immune response Mouse IgG1 is composed of two heavy chains and two light chains and it is involved in opsonization complement activation and antibody-dependent cell-mediated cytotoxicity It is also involved in the regulation of immune responses including the activation of T cells and the inhibition of B cell activation Mouse IgG1 is widely used in research and diagnostic applications including ELISA Western blotting and immunohistochemistry It is also used in therapeutic applications such as immunotherapy and vaccine development
Jackson Immuno Research Labs AMCA-AffiniPure Rabbit Anti-Mouse IgG F(ab')2 Fragment Specific (min X Hu Sr Prot)
AMCA-AffiniPure Rabbit Anti-Mouse IgG F(ab')2 Fragment Specific (min X Hu Sr Prot)
ABclonal Technology APC Rabbit anti-Mouse CD38 mAb
This gene encodes a non-lineage-restricted type II transmembrane glycoprotein that synthesizes and hydrolyzes cyclic adenosine 5 -diphosphate-ribose an intracellular calcium ion mobilizing messenger The release of soluble protein and the ability of membrane-bound protein to become internalized indicate both extracellular and intracellular functions for the protein This protein has an N-terminal cytoplasmic tail a single membrane-spanning domain and a C-terminal extracellular region with four N-glycosylation sites Knockout mice deficient for this gene display altered humoral immune responses In addition knockout mice exhibit higher locomotor activity and defects in nurturing and social behaviors
ABclonal Technology PE Rabbit anti-Mouse CD4 mAb
Predicted to enable several functions including interleukin-16 binding activity interleukin-16 receptor activity and protein homodimerization activity Involved in helper T cell enhancement of adaptive immune response Acts upstream of or within several processes including defense response to Gram-negative bacterium positive regulation of calcium-mediated signaling and positive regulation of peptidyl-tyrosine phosphorylation Located in endoplasmic reticulum external side of plasma membrane and membrane raft Is expressed in several structures including alimentary system brain genitourinary system hemolymphoid system and liver and biliary system Used to study type 1 diabetes mellitus Human ortholog(s) of this gene implicated in immunodeficiency 79 Orthologous to human CD4 (CD4 molecule)
ABclonal Technology PE Rabbit anti-Mouse CD94 mAb
CD94 is a 43 39 kD C-type lectin also known as Kp43 It is present on all NK cells NKT cells and a subset of CD8-positive T lymphocytes in most mouse strains CD94 is a type-II transmembrane protein with an extracellular lectin-like domain and a short cytoplasmic tail CD94 is expressed as a disulphide-linked heterodimer with a NKG2 subunit believed to mediate signal transduction When associated with NKG2A the complex triggers inhibition when associated with NKG2C the complex triggers stimulation The receptor complex of CD94 and NKG2 receptors bind to the ligand Qa-1 and are thought to play a role in maintaining self-tolerance in developing NK cells
Jackson Immuno Research Labs AffiniPure F(ab')2 Fragment Rabbit Anti-Mouse IgG F(ab')2 Fragment Specific (min X Hu Sr Prot)
AffiniPure F(ab')2 Fragment Rabbit Anti-Mouse IgG F(ab')2 Fragment Specific (min X Hu Sr Prot)
ABclonal Technology PE Rabbit anti-Mouse CD87 mAb
Predicted to enable enzyme binding activity protein domain specific binding activity and signaling receptor binding activity Predicted to be involved in several processes including negative regulation of apoptotic signaling pathway positive regulation of epidermal growth factor receptor signaling pathway and positive regulation of release of cytochrome c from mitochondria Is integral component of plasma membrane Is expressed in several structures including decidua early conceptus and spleen Human ortholog(s) of this gene implicated in rheumatoid arthritis Orthologous to human PLAUR (plasminogen activator urokinase receptor)
ABclonal Technology PE Rabbit anti-Mouse CD204 mAb
Enables amyloid-beta binding activity cargo receptor activity and low-density lipoprotein particle binding activity Involved in several processes including endocytosis positive regulation of cholesterol storage and positive regulation of macrophage derived foam cell differentiation Acts upstream of or within establishment of localization in cell and lipoprotein transport Located in plasma membrane Is expressed in several structures including alimentary system early conceptus limb neural tube and reproductive system Human ortholog(s) of this gene implicated in Barrett s esophagus arteriosclerosis and prostate cancer Orthologous to human MSR1 (macrophage scavenger receptor 1)
ABclonal Technology PE Rabbit anti-Mouse CD62L mAb
Enables cell adhesion molecule binding activity Acts upstream of or within response to ATP Located in external side of plasma membrane Is expressed in brain brainstem submandibular gland epithelium and testis Used to study type 1 diabetes mellitus Human ortholog(s) of this gene implicated in Crohn s disease IgA glomerulonephritis and ulcerative colitis Orthologous to human SELL (selectin L)
ABclonal Technology PE Rabbit anti-Mouse/Rat CD54
This gene encodes an integral membrane protein that binds leukocyte adhesion protein LFA-1 It participates in the innate immune response
ABclonal Technology PE Rabbit anti-Mouse/Rat CD54
This gene encodes an integral membrane protein that binds leukocyte adhesion protein LFA-1 It participates in the innate immune response